pentobarbital will minimize the extent or effect of montelukast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unfamiliar.
pentobarbital will reduce the level or influence of clarithromycin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
pentobarbital boosts consequences of ifosfamide by influencing hepatic enzyme CYP2B6 metabolism. Use Caution/Observe. Coadministration of ifosfamide with CYP2B6 inducers may boost metabolism of ifosfamide to its metabolite. Check for increased effects/toxicities if combined with CYP2B6 inducers.
pentobarbital will lessen the level or outcome of bazedoxifene/conjugated estrogens by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lower the extent or result of amiodarone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will decrease the level or influence of ramelteon by influencing hepatic enzyme CYP2C9/ten metabolism. Small/Importance Unknown.
pentobarbital will decrease the level or outcome of tamoxifen by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
With therapeutic doses of TCAs, barbiturates enhance metabolism and decrease blood concentrations of TCAs.
pentobarbital will lower the extent or influence of maraviroc by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will minimize the level or impact of venetoclax by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
Contraindicated. Coadministration of doravirine with a strong CYP3A inducer may lessen doravirine plasma concentrations and/or results. Likely for loss of virologic response and doable resistance to doravirine.
Next oral or parenteral administration, barbiturates commonly cross the placental barrier and they are dispersed in the course of fetal tissues with optimum concentrations located in the placenta, fetal liver, get more info and brain; fetal blood ranges method maternal blood degrees following parenteral administration
pentobarbital will lower the level or impact of paclitaxel protein certain by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unknown.
Monoamine oxidase inhibitors (MAOI) may perhaps inhibit barbiturate metabolism and prolong barbiturate consequences; monitor intently